Motrin (Ibuprofen) is used in adults for relief of the symptoms of rheumatoid arthritis and osteoarthritis, the treatment of menstrual pain, and the relief of mild to moderate pain.

In children of 6 months and older Motrin (Ibuprofen) may be given to reduce fever and to relieve mild to moderate pain.

Motrin (Ibuprofen) is also used to relieve the symptoms of juvenile arthritis.

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MOTRIN (IBUPROPHEN) INFORMATION

Taking Motrin (Ibuprophen)

In the case of minor aches, mild to moderate pain, menstrual cramps and fever the usual adult dose of motrin (ibuprofen) is 200 or 400 mg every 4 to 6 hours.
Arthritis is treated with 300 to 800 mg motrin (ibuprofen) 3 or 4 times a day.
When under the supervision of a physician, the daily maximum dose of motrin (ibuprofen) is 3.2 g. Otherwise, the maximum daily dose of motrin (ibuprofen) is 1.2 g daily.
You should not use motrin (ibuprofen) for more than 10 days for the treatment of pain or more than 3 days for the treatment of a fever unless directed by a physician.

Children from 6 months to 12 years of age usually are given 5-10 mg/kg of motrin (ibuprofen) every 6-8 hours when treating fever and pain. The maximum daily dose is 40 mg/kg.

Juvenile arthritis is treated with 20 to 40 mg/kg/day in 3 to 4 divided doses.

Motrin (ibuprofen) should be taken with meals.

Side effects

The most common side effects when taking motrin (ibuprofen) are rash, ringing in the ears, headaches, dizziness, drowsiness, abdominal pain, nausea, diarrhea, constipation and heartburn. Ibuprofen may cause ulceration of the stomach or intestine, and the ulcers may bleed. Sometimes, ulceration and bleeding can occur without abdominal pain, and black tarry stools, weakness, and dizziness upon standing (orthostatic hypotension) may be the only signs of a problem. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with pre-existing impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously. People who are allergic to other NSAIDs, including aspirin, should not use motrin (ibuprofen). Patients with asthma are more likely to experience an allergic reaction to motrin (ibuprofen) and other NSAIDs.

Precautions

Before taking motrin (ibuprofen) tell your prescriber if you are allergic to motrin (ibuprofen), aspirin or other medications for pain or arthritis, or any other drugs. Tell your prescriber what prescription and non prescription medications you are taking, especially anticoagulants ('blood thinners') such as warfarin (Coumadin), aspirin, atenolol (Tenormin), carteolol (Cartrol), cyclosporine (Neoral, Sandimmune), digoxin (Lanoxin), diuretics ('water pills'), labetalol (Normodyne, Trandate), lithium (Eskalith, Lithobid), medications for arthritis or diabetes, methotrexate, metoprolol (Lopressor), nadolol (Corgard), phenytoin (Dilantin), probenecid (Benemid), and vitamins. Do not take aspirin or acetaminophen when taking motrin (ibuprofen) unless advised to do so by your doctor. Tell your doctor if you have or have ever had liver, heart, or kidney disease; high blood pressure; any stomach problems; or any other gastrointestinal disease.
Tell your doctor if you are pregnant or plan to become pregnant, taking motrin (ibuprofen) is not recommended if you are pregnant. Tell your doctor if you are breast-feeding, you should avoid taking motrin (ibuprofen) if you are breast feeding. If you become pregnant while taking motrin (ibuprofen), consult with your doctor. If you are having surgery, including dental surgery, tell the doctor or dentist that you are using motrin (ibuprofen).
Motrin (ibuprofen) may make you drowsy. Do not drive a car or operate machinery until you know how motrin (ibuprofen) affects you. If you drink 3 or more alcohol drinks every day, ask your doctor if you should take motrin (ibuprofen). You should not drink alcoholic beverages while taking motrin (ibuprofen).

Drug Interactions

Motrin (ibuprofen) may interact with other drugs. motrin (ibuprofen) may increase your blood levels of lithium (Eskalith). Increased levels of lithium may lead to lithium toxicity. motrin (ibuprofen) may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. When motrin (ibuprofen) is used in combination with aminoglycosides (e.g., gentamicin) the blood levels of the aminoglycoside may increase. This may lead to aminoglycoside-related side effects. Patients taking oral blood thinners or anticoagulants (e.g., warfarin) should avoid motrin (ibuprofen) because ibuprofen also thins the blood, excessive blood thinning may lead to bleeding.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Missed dose

Take the missed motrin (ibuprofen) dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed motrin (ibuprofen) dose and continue your regular dosing schedule. Do not double up dose to make up.

Motrin (Ibuprophen) Storage

Motrin (Ibuprofen) should be stored at room temperature, between 15-30°C (59-86°F).

Keep motrin (ibuprofen) out of the reach of children.

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